Translational cancer research has taken giant leaps since appearing in the scientific literature at the beginning of the 21st century. It progressed from identifying a single mutation driving cancer to the high-throughput next-generation whole-genome sequencing analyses. Recent advances in omics have broadened our knowledge of the processes underlying cancer treatment.

In recognition of its importance, we have recently launched a new cross-journal article collection on Translational Oncology, guest edited by Prof Tommaso Dragani. As part of the collection, in a Forum Article, 8 cancer research experts highlight major translational advances in colorectal, ovarian, breast, lung, and prostate cancer research.