Image-guided biopsy. Some types of biopsies can be image-guided. When your doctor cannot feel a tumour or when the area is deeper inside the body but appears on an imaging scan, he or she may use an image-guided approach. Your doctor guides a needle to the location with the help of an imaging technique during this procedure. Using a fine needle, core or vacuum-assisted biopsy, your doctor can do an image-guided biopsy. On the amount of tissue needed, possible diagnoses and other factors, this depends. On the location and other factors, the type of imaging used by your doctor depends. Ultrasound, Fluoroscopy, Computed Tomography (CT) scan, X-ray and Magnetic Resonance Imaging (MRI) scan are the various types of imaging scans.